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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Pediatric Ophthalmology</journal-id><journal-title-group><journal-title xml:lang="en">Russian Pediatric Ophthalmology</journal-title><trans-title-group xml:lang="ru"><trans-title>Российская педиатрическая офтальмология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1993-1859</issn><issn publication-format="electronic">2412-432X</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">37435</article-id><article-id pub-id-type="doi">10.17816/rpoj37435</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">DRY EYE SYNDROME ASSOCIATED WITH ENDOGENOUS UVEITIS IN THE CHILDREN</article-title><trans-title-group xml:lang="ru"><trans-title>СИНДРОМ СУХОГО ГЛАЗА ПРИ ЭНДОГЕННЫХ УВЕИТАХ У ДЕТЕЙ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Katargina</surname><given-names>L. A</given-names></name><name xml:lang="ru"><surname>Катаргина</surname><given-names>Л. А</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., зам. дир. по научной работе, рук. отд. патологии глаз у детей</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shestova</surname><given-names>Yu. P</given-names></name><name xml:lang="ru"><surname>Шестова</surname><given-names>Ю. П</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отд. патологии глаз у детей</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Denisova</surname><given-names>E. V</given-names></name><name xml:lang="ru"><surname>Денисова</surname><given-names>Елена Валерьевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, ст. науч. сотр. отд. патологии глаз у детей</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Helmholtz Research Institute of Eye Diseases</institution></aff><aff><institution xml:lang="ru">ФГБУ «Московский НИИ глазных болезней им. Гельмгольца» Минздравсоцразвития России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2012</year></pub-date><volume>7</volume><issue>2</issue><issue-title xml:lang="en">NO2 (2012)</issue-title><issue-title xml:lang="ru">№2 (2012)</issue-title><fpage>17</fpage><lpage>20</lpage><history><date date-type="received" iso-8601-date="2020-07-21"><day>21</day><month>07</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, ООО "Эко-Вектор"</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ruspoj.com/1993-1859/article/view/37435">https://ruspoj.com/1993-1859/article/view/37435</self-uri><abstract xml:lang="en"><p>A total of 47 children with uveitis of different localization and etiology were available for the estimation of overall lacrimation and stability of the precorneal lacrimal film. The study demonstrated a high frequency of dry eye syndrome (DES) diagnosed in 85% of the patients suffering the moderately or strongly impaired lacrimation and stability of the precorneal lacrimal film (in 46% and 28% of the cases respectively). The multi-factor character of dry eye syndrome was documented. Its development was shown to be related to the frequency of relapses of uveitis, the presence of a systemic rheumatoid disease, local anti-inflammatory and hypotensive therapy, systemic immunosuppressive treatment, and/or surgical interventions on the anterior parts of the eyes. DES was shown to be associated with the dystrophic changes in the cornea. The necessity of early diagnostics of dry eye syndrome in the patients presenting with uveitis and of prescription of tear replacement therapy is substantiated.</p></abstract><trans-abstract xml:lang="ru"><p>У 47 детей с эндогеннымиувеитами различной локализации и этиологии изучены суммарная слезопродукция и стабильность прероговичной слезной пленки. Отмечена высокая частота развития синдрома сухого глаза (ССГ) (85%), в том числе с умеренной и тяжелой степенью снижения слезопродукции в 28% случаев, стабильности слезной пленки — в 46%. Установлен мультифакториальный характер ССГ при увеитах. Выявлена связь его развития с длительностью и частотой рецидивов увеита, наличием системного ревматического заболевания, местной противовоспалительной и гипотензивной терапией, системным иммуносупрессивным лечением, проведением хирургических вмешательств на переднем отрезке глаза. Обнаружена связь развития дистрофических изменений роговицы с ССГ. Обоснована необходимость ранней диагностики ССГ при увеитахи назначения слезозаместительной терапии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>endogenous uveitis in the children</kwd><kwd>dry eye syndrome</kwd><kwd>overall lacrimation</kwd><kwd>stability of the precorneal lacrimal film</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эндогенные увеиты у детей</kwd><kwd>синдром сухого глаза</kwd><kwd>суммарная слезопродукция</kwd><kwd>стабильность прероговичной слезной пленки</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Бржеский В.В., Сомов Е.Е. Роговично-конъюнктивальный ксероз (диагностика, клиника, лечение). — 2-е изд. — СПб., 2003.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Карагулян Н.А. 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