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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Pediatric Ophthalmology</journal-id><journal-title-group><journal-title xml:lang="en">Russian Pediatric Ophthalmology</journal-title><trans-title-group xml:lang="ru"><trans-title>Российская педиатрическая офтальмология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1993-1859</issn><issn publication-format="electronic">2412-432X</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">37602</article-id><article-id pub-id-type="doi">10.17816/rpoj37602</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">THE BASIC STRATEGY OF DEVELOPMENT AN ANIMAL MODEL OF RETINOPATHY OF PREMATURITY</article-title><trans-title-group xml:lang="ru"><trans-title>ОСНОВНЫЕ ПРИНЦИПЫ ЭКСПЕРИМЕНТАЛЬНОГО МОДЕЛИРОВАНИЯ РЕТИНОПАТИИ НЕДОНОШЕННЫХ НА ЖИВОТНЫХ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Katargina</surname><given-names>L. A</given-names></name><name xml:lang="ru"><surname>Катаргина</surname><given-names>Л. А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Osipova</surname><given-names>N. A</given-names></name><name xml:lang="ru"><surname>Осипова</surname><given-names>Н. А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Federal state budgetary institution «Moscow Helmholtz Institute of Ophthalmology», Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ «Московский НИИ глазных болезней им. Гельмгольца» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2014</year></pub-date><volume>9</volume><issue>1</issue><issue-title xml:lang="en">NO1 (2014)</issue-title><issue-title xml:lang="ru">№1 (2014)</issue-title><fpage>56</fpage><lpage>60</lpage><history><date date-type="received" iso-8601-date="2020-07-21"><day>21</day><month>07</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, ООО "Эко-Вектор"</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ruspoj.com/1993-1859/article/view/37602">https://ruspoj.com/1993-1859/article/view/37602</self-uri><abstract xml:lang="en"><p>This review presents the foundation of the development of an animal model of retinopathy of prematurity and a description of the existing animal models. The review also discusses the importance of animal models for the study of the pathogenesis of retinopathy of prematurity and the search for new approaches to the treatment of this disease.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре представлены основы моделирования ретинопатии недоношенных на животных и дано описание существующих моделей. Обсуждается значение создания и совершенствования моделей с использованием животных в плане изучения патогенеза ретинопатии недоношенных и поиска новых подходов к лечению данного заболевания.</p></trans-abstract><kwd-group xml:lang="en"><kwd>retinopathy of prematurity</kwd><kwd>oxygen</kwd><kwd>animal models</kwd><kwd>experimental research</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ретинопатия недоношенных</kwd><kwd>кислород</kwd><kwd>животные модели</kwd><kwd>экспериментальные исследования</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Dorfman A., Dembinska O., Chemtob S., Lachapelle P. Early manifestations of postnatal hyperoxia on the retinal structure and function of the neonatal rat. Invest. Ophthalmol. Vis. Sci. 2008; 49(1): 458—66.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Dorfman A.L., Cuenca N., Pinilla I., Chemtob S., Lachapelle P. 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