Russian Pediatric OphthalmologyRussian Pediatric OphthalmologyРоссийская педиатрическая офтальмология1993-18592412-432XEco-Vector3954510.18821/1993-1859-2017-12-1-27-34ArticlesСтатьиReview ArticleTHE EVALUATION OF THE STATE OF CHOROID IN THE PATIENTS PRESENTING WITH UVEITIS OF DIFFERENT ETIOLOGY BASED ON THE RESULTS OF OPTICAL COHERENCE TOMOGRAPHYСОСТОЯНИЕ СОСУДИСТОЙ ОБОЛОЧКИ ГЛАЗА ПРИ УВЕИТАХ РАЗЛИЧНОЙ ЭТИОЛОГИИ ПО ДАННЫМ ОПТИЧЕСКОЙ КОГЕРЕНТНОЙ ТОМОГРАФИИKatarginaL. AКатаргинаЛ. АDenisovaE. VДенисоваЕ. ВNovikovaO. VНовиковаОльга Владимировна

аспирант отдела патологии глаз у детей ФГБУ «Московский НИИ глазных болезней им. Гельмгольца» Минздрава России, 105062, Москва.

olganovv@mail.ruThe Helmholtz Moscow Research Institute of Eye Diseases, Russian Ministry of healthФГБУ «Московский НИИ глазных болезней им. Гельмгольца» Минздрава России15032017121VOL 12, NO1 (2017)ТОМ 12, №1 (2017)273422072020Copyright ©; 2017, Eco-VectorCopyright ©; 2017, ООО "Эко-Вектор"2017Eco-VectorООО "Эко-Вектор"https://ruspoj.com/1993-1859/article/view/39545

The evaluation of the state of choroid in the patients presenting with uveitis is one of the promising directions in modern ophthalmological diagnostics because it provides the opportunity for obtaining the objective quantitative characteristics of the activity of the inflammatory process and thereby makes it possible to more accurately estimate the effectiveness of the treatment. It has been shown that the thickness of choroid considerably increases during the acute phase of Vogt-Koyanangi-Harada disease, active uveitis associated with Behcet’s disease, sarcoidosis, and toxoplasmosis and returns to the normal value under the influence of the treatment. In certain cases, the thickness of choroid decreases in comparison with that in the healthy eyes. The thinning of choroid was documented also at the stage of the clinical remission of birdshot retinochoroidopathy, Fuchs syndrome-associated uveitis, posterior non-infectious and idiopathic pan-uveites. It can possibly be the result of the atrophy of choroid due to the inflammatory and ischemic processes. Unfortunately, the available literature data have been obtained in disconnected studies of the choroid of the patients suffering from uveitis that involved only the small number of the patients and were confined to a few selected etiological and pathogenetic structural variants of this condition.

Оценка состояния хориоидеи при увеитах - одно из перспективных направлений современной диагностики в офтальмологии, поскольку дает возможность получить объективные количественные данные, отражающие активность воспалительного процесса и позволяющие оценить эффективность проводимого лечения. Установлено, что для глаз пациентов с острой фазой болезни Фогта-Коянаги-Харада, активным увеитом при болезни Бехчета, а также с саркоидозом и токсоплазмозом характерно значительное увеличение толщины хориоидеи и ее нормализация на фоне лечения, а в ряде случаев - уменьшение по сравнению со здоровыми глазами. Уменьшение толщины сосудистой оболочки глаза наблюдалось также в стадии клинической ремиссии хориоретинопатии «выстрел дробью», увеита при синдроме Фукса, задних неинфекционных и идиопатических панувеитов, что, вероятно, обусловлено атрофией сосудистой оболочки в результате воспалительного и ишемического процесса. К сожалению, имеющиеся в доступной литературе сведения представляют собой результаты единичных исследований сосудистой оболочки глаза при увеитах, ограниченных как по количеству обследованных пациентов, так и по этиологической структуре увеитов.

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