Russian Pediatric OphthalmologyRussian Pediatric OphthalmologyРоссийская педиатрическая офтальмология1993-18592412-432XEco-Vector59586710.17816/rpoj595867Case reportsКлинические случаиResearch ArticleCongenital cataract associated with COVID-19 infectionВрождённая катаракта, ассоциированная с инфекцией COVID-19https://orcid.org/0000-0001-8801-8368KruglovaTatyana B.КругловаТатьяна Борисовна
Russian Federation

MD, Dr. Sci. (Med.)

д.м.н.

krugtb@yandex.ruhttps://orcid.org/0000-0001-9906-4706EgyanNaira S.ЕгиянНаира Семеновна
Russian Federation

MD, Cand. Sci. (Med.)

к.м.н.

nairadom@mail.ruhttps://orcid.org/0000-0001-6523-5191DemchenkoElena N.ДемченкоЕлена Николаевна
Russian Federation

MD, Cand. Sci. (Med.)

к.м.н.

dem-andrej@yandex.ruHelmholtz National Medical Research Center of Eye DiseasesНМИЦ глазных болезней им. Гельмгольца161220231842052122609202302102023Copyright ©; 2023, Eco-VectorCopyright ©; 2023, Эко-Вектор2023Eco-VectorЭко-Векторhttps://creativecommons.org/licenses/by-nd/4.0/https://ruspoj.com/1993-1859/article/view/595867

AIM: To describe cases of COVID-19-induced congenital pathology of the lens and eye in children.

MATERIALS AND METHODS: Nine children (9 eyes) aged 3–6 months with congenital cataract (СC), whose mothers had COVID-19 during pregnancy, were examined.

RESULTS: All children had unilateral CC, with heterogeneous turbidity. Changes in the shape, volume, and structure of the capsule sac were often combined with microphthalmia (66.7%) and primary persistent vitreous body syndrome (PPGST) (88.9%).

CONCLUSION: The results revealed the possibility of the unilateral development congenital pathology of the lens with the presence of concomitant pathology: microphthalmos, PPGST syndrome in children born to mothers who had SARS-CoV-2 infection during pregnancy. Given the risk of transplacental transmission of the coronavirus from a pregnant woman to a fetus with СC development, these children need a more detailed examination in the first month of life for timely detection of pathology and provision of treatment. Surgical treatment of this pathology often requires a nonstandard individual approach to each stage of the operation and management of the postoperative period.

Цель. Описание случаев ковид-индуцированной врождённой патологии хрусталика и глаза у детей.

Материалы и методы. Обследовано 9 детей (9 глаз) в возрасте 3–6 месяцев с врождённой катарактой, матери которых переболели COVID-19 во время беременности.

Результаты. У всех детей врождённая катаракта была односторонней с неоднородным характером помутнения, изменением формы, объёма и структуры капсульного мешка, часто сочетающаяся с микрофтальмом (66,7%) и синдромом первичного персистирующего гиперпластического стекловидного тела (ППГСТ) (88,9%).

Заключение. Показана возможность развития врождённой патологии хрусталика в основном одностороннего характера с наличием сопутствующей патологии: микрофтальм, синдром ППГСТ у детей, рождённых матерями, перенёсшими во время беременности инфекцию вирусом SARS-CoV-2. Учитывая риск трансплацентарного пути передачи коронавируса от беременной женщины плоду с развитием врождённой катаракты, эти дети нуждаются в более детальном обследовании уже в первые месяцы жизни для своевременного выявления патологии и проведения лечения. Хирургическое лечение данной патологии часто требует нестандартного, индивидуального подхода к каждому этапу операции и ведению послеоперационного периода.

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