Assessing risks of circulatory disorders among adults exposed to ambient air chemical contamination when living in the perm region

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Abstract

Introduction. It is vital to study circulatory diseases as they account for the greatest share in causes of death in Russia (about 55%). Also, environmental factors contribute significantly to morbidity with circulatory diseases. It is important to reveal chemicals that exert their impacts on pathology occurrence in the circulatory system; should such impacts be eliminated or reduced, it will make for a decrease in morbidity and mortality among the population caused by the nosologies being considered in the present work.

Material and methods. We took data on chemical contamination of ambient air and data on primary morbidity as per the “diseases of the circulatory system” category among the adult population living in the Perm region over 2013-2017 as or initial data. All the data were processed with many techniques including hygienic examination, health risk assessment under chronic inhalation exposure, and mathematic modeling within the “health - environment” system.

Results. Our research results allowed establishing that there was an ascending trend in primary morbidity with circulatory diseases among the population living in the Perm region. We revealed that phenol concentrations amounted up to 6.67 MPC average daily, and benzene ones, up to 2.37 MPC average daily; simultaneously, we revealed unacceptable risk regarding circulatory diseases (harm index (HI) was up to 1.9), and the greatest contribution into it was made by phenol (up to 78.52%) and benzene (up to 75.59%). Mathematic modeling allowed establishing there was an authentic and relevant cause-and-effect relation between primary morbidity with circulatory diseases among the adult population and ambient air contamination with phenol.

Conclusions. We revealed phenol and benzene concentrations in ambient air which were significantly higher than MPC; identified and parameterized an authentic cause-and-effect relation between ambient air contamination with phenol and circulatory diseases.

About the authors

Kristina V. Chetverkina

Federal Scientific Center for Medical and Preventive Health Risk Management Technologies

Author for correspondence.
Email: chetverkina@fcrisk.ru
ORCID iD: 0000-0002-1548-228X

MD, Senior Researcher of the Health Risk Analysis Department, Federal Scientific Center for Medical and Preventive Health Risk Management Technologies, Perm, 614045, Russian Federation.

e-mail: chetverkina@fcrisk.ru

Russian Federation

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