Stereotaxic Method of Brain Loci Localization: The Alternative Approaches

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Abstract

The article discusses the possibilities of the alternative methods for determining the localization of small-sized brain cell formations in animals. The advantages of the electrophysiological approach used in localization of the tested nuclear structures of the brain, their selective damage and subsequent histological verification of the location and size of the damage to the brain tissue are shown. Methodological recommendations are proposed that provide an error-free determination of the coordinates of the tested brain structures, which leads to a significant reduction in the time for conducting planned studies and the costs of their implementation due to the absence of the need to include a large number of animals in the experiment.

About the authors

S. V. Albertin

Pavlov Institute of Physiology, Russian Academy of Sciences

Author for correspondence.
Email: albertinsv@infran.ru
Russia, St. Petersburg

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