Synthesis of silicon dioxide xerogels and their sorption- desorption properties with respect to nicotine and glycols

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Abstract

Composites based on silicon dioxide xerogels containing glycerol and nicotine were prepared by hydrolysis of tetraethoxysilane by a single-stage synthesis and two-stage sorption method with a single-stage glycerol sorption in relation to the sorbent reaches 3: 1 by weight. The kinetics of release (desorption) of nicotine from an aerosol mixture with glycols has been studied. The synthesized sorbent is promising for use in aerosol generating systems, as well as carriers and delivery systems for biologically active substances and medicines.

About the authors

S. G Grigoryan

Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry

Email: grigstepan@yahoo.com

E. H Hakopyan

Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry

R. M Hakobyan

Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry

Z. M Farmazyan

Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry

M. L Atabekyan

Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry

V. O Topuzyan

Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry

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