Enviar artigo por via de e-mail Three-component synthesis and antibacterial activity of 5-Aryl-4-acyl-3-hydroxy-1-(4-methoxyphenyl)-3-pyrroline-2-ones
- Autores: Kasimova N.N.1, Maiamsina O.O.1,2, Dubrovina S.S.1, Gein V.L.1
-
Afiliações:
- Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
- Perm State Medical University named after Academician E. A. Wagner of the Ministry of Health of the Russian Federation
- Edição: Volume 95, Nº 5-6 (2025)
- Páginas: 191-198
- Seção: Articles
- URL: https://ruspoj.com/0044-460X/article/view/688760
- DOI: https://doi.org/10.31857/S0044460X25050034
- EDN: https://elibrary.ru/FISLVD
- ID: 688760
Citar
Texto integral
Acesso aberto
Acesso está concedido
Acesso é pago ou somente para assinantes
Resumo
A series of new 5-aryl-4-acyl-3-hydroxy-1-(4-methoxyphenyl)-3-pyrrolin-2-ones was synthesized by the reacting of methyl esters of aroylpyruvic acids with a mixture of aromatic aldehyde and p-anisidine. Antibacterial activity of the obtained compounds was studied in vitro against Staphylococcus aureus and Escherichia coli strains.
Texto integral
Sobre autores
N. Kasimova
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: pufmail135@gmail.com
ORCID ID: 0009-0001-6348-7333
Rússia, Perm, 614990
O. Maiamsina
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation; Perm State Medical University named after Academician E. A. Wagner of the Ministry of Health of the Russian Federation
Email: pufmail135@gmail.com
Rússia, Perm, 614990; Perm, 614990
S. Dubrovina
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Email: pufmail135@gmail.com
Rússia, Perm, 614990
V. Gein
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Email: pufmail135@gmail.com
ORCID ID: 0000-0002-8512-0399
Rússia, Perm, 614990
Bibliografia
- Afsah E.M., Abdelmageed S.M. // J. Heterocyclic Chem. 2020. Р. 1. doi: 10.1002/jhet.4098
- Manta S., Kollatos N., Mitsos C., Chatzieffraimidi G.-A., Papanastasiou I., Gallos J.K., Komiotis D. // Mini-Rev. Med. Chem. 2020. Vol. 20. N 10. P. 818. doi 10.2174/ 1389557520666200103123114
- Гейн О.Н., Рубцова Д.Д., Гейн В.Л. // Хим.-фарм. ж. 2022. Т. 56. № 12. С. 35. doi: 10.30906/0023-1134-2022-56-12-35-37
- Cusumano A.Q., Pierce J.G. // Bioorg. Med. Chem. Lett. 2018. Vol. 28. N 16. P. 2732. doi 10.1016/ j.bmcl.2018.02.047
- Joksimović N., Petronijević J., Janković N., Baskić D., Popović S., Todorović D., Matic S., Bogdanovic G.A., Vranes M., Tot A., Bugarčić Z. // Bioorg. Chem. 2019. Vol. 88. P. 102954. doi: 10.1016/j.bioorg.2019.102954
- Ahankar H., Ramazani А., Slepokura К., Lis Т., Joo S.W. // Green Chem. 2016. N 18. P. 3582. doi: 10.1039/c6gc00157b
- Машковский М.Д. Лекарственные средства. М.: Новая волна, 2024. 1216 с.
- Paguigan N.D., Yan Y., Karthikeyan M., Chase K., Carter J., Leavitt L.S., Lim A.L., Lin Z., Memon T., Christensen S., Bentzen B.H., Schmitt N., Reilly C.A., Teichert R.W., Raghuraman S., Olivera B.M., Schmidt E.W. // ACS Chem. Biol. 2021. Vol. 16. N 9. P. 1654. doi: 10.1021/acschembio.1c00328
- Duncan L.F., Wang G., Ilyichova O.V., Dhouib R., Totsika M., Scanlon M.J., Heras B., Abbott B.M. // Bioorg. Med. Chem. 2021. Vol. 45. P. 116315. doi 10.1016/ j.bmc.2021.116315
- Brown D.W., Denman C., OʼDonnell H. // J. Chem. Soc. (C). 1971. P. 3195. doi: 10.1039/J39710003195
- Ma K., Wang P., Fu W., Wan X., Zhou L., Chu Y., Ye D. // Bioorg. Med. Chem. Lett. 2011. Vol. 21. N 22. P. 6724. doi: 10.1016/j.bmcl.2011.09.054
- Gein V.L., Chalkov D.V., Romanova A.V., Bobrovskaya O.V., Chashchina S.V., Dmitriev M.V. // Russ. J. Org. Chem. 2025. Vol. 61. N 1. P. 16. doi: 10.1134/S1070428025010026
- Гейн В.Л., Гейн Л.Ф., Безматерных Э.Н., Шуров С.Н. // ЖОХ. 2000. Т. 70. Вып. 10. С. 1692.
- Руководство по проведению доклинических исследований лекарственных средств / Под ред. А.Н. Миронова. М.: Гриф и К, 2012. Ч. 1. 944 с.
Arquivos suplementares
