Multicomponent synthesis of functionalized 2-amino-4H-pyrans initiated by the Knoevenagel reaction

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Abstract

The multicomponent condensation of aldehydes, malononitrile derivatives, 1,3-dicarbonyl compounds of the carbo- and heterocyclic series, and alkyl halides has been studied. The transformation is initiated by the Knoevenagel reaction and leads to the formation of functionally substituted condensed 2-amino- 4 H-pyrans. The structure of a number of products was studied by X-ray diffraction.

About the authors

I. V Dyachenko

Lugansk State Pedagogical University

Email: nenajdenko@gmail.com

V. D Dyachenko

Lugansk State Pedagogical University

Email: nenajdenko@gmail.com

P. V Dorovatovskii

National Research Center “Kurchatov Institute”

Email: nenajdenko@gmail.com

V. N Khrustalev

Peoples’ Friendship University of Russia (RUDN University);Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Email: nenajdenko@gmail.com

V. G Nenajdenko

Lomonosov Moscow State University

Email: nenajdenko@gmail.com

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