Application of the Knorr reaction for the directional synthesis of pyrazole derivative as a biologically active co-ligandes of gold glyco-nanoparticles

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Abstract

Based on the reaction of acetylacetone with 6-mercaptohexanoic and 11-mercaptoundecanoic acid hydrazides, a method was developed for the synthesis of previously unknown 1-(ω-mercaptoacyl)-3,5-dimethylpyrazole as promising сo-ligand for the preparation of gold glyco-nanoparticles for biomedical purposes.

About the authors

A. Y. Ershov

Institute of Macromolecular Compounds of Russian Academy of Sciences

Email: ershov305@mail.ru

A. A. Martynenkov

Institute of Macromolecular Compounds of Russian Academy of Sciences

I. V. Lagoda

State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation

A. A. Batyrenko

State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation

References

  1. Ling L.E., Lee W.-C. Curr. Pharm. Biotech. 2011, 12, 2190-2202. doi: 10.2174/138920111798808257
  2. Rostami H., Shiri L., Khani Z. Tetrahedron. 2022, 110, 132688. doi: 10.1016/j.tet.2022.132688
  3. Федянин М.Ю., Хмелькова Д.Н., Серебрийская Т.С., Никольская Т.А., Тюляндин С.А. Усп. Молекул. Онкол. 2015, 2, 027-038.
  4. Fedyanin M.Yu., Khmelkova D.N., Serebriyskaya T.S., Nikolskaya T.A., Tyulyandin S.A. Adv. Mol. Oncol. 2015, 2, 027-032. doi: 10.17650/2313-805X.2015.2.1.027-038
  5. Banday A.H., Saeed B.A., Al-Masoudi N.A. Anti-Canсer Agen. Med. Chem. 2021, 21, 1671-1679. doi: 10.2174/1871520620999201124213655
  6. Naim M.J., Alam O., Nawaz F., Alam J., Alam P. J. Pharm. Bioallied Sci. 2016, 8, 2-17. doi: 10.4103/0975-7406.171694
  7. Adak A.K., Yu C.-C., Lin C.-C. Glycochemical Synthesis: Strategies and Applications. Eds. S.-C. Hung, M.M.L. Zulueta. Hoboken: John Wiley & Sons Inc. 2016. doi: 10.1002/9781119006435.ch16
  8. Knorr L. Ber. 1883, 16, 2597-2599. doi: 10.1002/cber.188301602194.
  9. Jazayeri M.H., Amani H., Pourfatollah A.A., Avan A., Ferns G.A., Pazoki-Toroudi H. Cancer Gene Ther. 2016, 23, 365-369. doi: 10.1038/cgt.2016.42
  10. Ершов А.Ю., Мартыненков А.А., Лагода И.В., Копаница М.А., Зарубаев В.В., Слита А.В., Бучков Е.В., Панарин Е.Ф., Якиманский А.В. ЖОХ. 2021, 91, 1459-1464.
  11. Ershov A.Y., Martynenkov A.A., Lagoda I.V., Kopanitsa M.A., Zarubaev V.V., Slita A.V., Buchkov E.V., Panarin E.F., Yakimansky A.V. Russ. J. Gen. Chem. 2021, 91, 1459-1464. doi: 10.1134/S1070363221090188
  12. Ershov A.Y., Martynenkov A.A., Lagoda I.V., Kopanitsa M.A., Yakimansky A.V. ChemestrySelect. 2019, 44, 12938-12941. doi: 10.1002/slct.201902942

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