CLINICAL TOXICOLOGY AND FORENSIC ASPECTS OF THE EVALUATION OF THE TOXIC EFFECT OF ETHANOL IN CHILDREN

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Abstract

The article presents the analysis of domestic and foreign literature on toxic effects of ethanol in children, statistics and the results of forensic investigations of children with the presence of ethanol in blood, forensic chemical and chemical toxicological studies of biological fluids taken from children and adolescents aged from 0 to 17 years and examined in the Bureau of Forensic Medical Expertise of the Moscow Region in 2003 – 2017, as well as clinical and statistical analysis of cases of ethanol poisoning in adolescents hospitalized in the toxicological department of intensive care of Moscow City Clinical Hospital № 5 in 2012 – 2015.

About the authors

V. A. Klevno

Bureau of Forensic Medical Expertise of the Moscow Region; M.F.Vladimirsky Moscow Regional Research Clinical Institute

Author for correspondence.
Email: vladimir.klevno@yandex.ru

111401, Moscow;

129110, Moscow.

Russian Federation

Yu. N. Ostapenko

Research and Applied Toxicology Center of the Federal Medical and Biological Agency; N.V. Sklifosovsky Research Institute for Emergency Medicine, Healthcare Department of Moscow

Email: rtiac@mail.ru

129090, Moscow;

129090, Moscow.

Russian Federation

A. V. Maksimov

Bureau of Forensic Medical Expertise of the Moscow Region; M.F.Vladimirsky Moscow Regional Research Clinical Institute

Email: maksimov@sudmedmo.ru

111401, Moscow;

129110, Moscow.

Russian Federation

References

  1. Toxic effect of alcohol / Federal clinical recommendations of Interregional charitable public organization «Association of clinical toxicologists» ed. Ostapenko Yu.N. - Moscow, 20 - 50 p.(in Russian).
  2. Nuzhnii V.P. Mechanisms and clinical manifestations of the toxic effect of alcohol: guide to addiction / ed. Ivanez N.N. M.: Medical Practice, 20 Vol. 1: 74-94 (in Russian).
  3. Luzhnikov E.A., Sukhodolova G.N. Acute poisoning in adults and children. Eksmo Ltd., 20- 560 p. (in Russian).
  4. Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 28th Annual Report. Bronstein A.C., Spyker D.A., Cantilena L.R. Jr, Green J.L., Rumack B.H., Dart R.C. Clin Toxicol (Phila). 2011; Dec; 49(10):910 - doi: 10.3109/15563650.2015.1102927.
  5. HYPERLINK «http://www.uptodate.com.ololo.sci-hub.io/contents/ethanol-intoxication-inchildren-epidemiology-estimation-of-toxicity-andtoxic-effects/abstract/2» Vogel C., Caraccio T., Mofenson H., Hart S. Alcohol intoxication in young children. J Toxicol Clin Toxicol 1995; 33: PMID: 7837310.
  6. HYPERLINK «http://www.uptodate.com.ololo.sci-hub.io/contents/ethanol-intoxicationin-children-epidemiology-estimation-oftoxicity-and-toxic-effects/abstract/3» Miller M., Borys D., Morgan D. Alcohol-based hand sanitizers and unintended pediatric exposures: a retrospective review. Clin Pediatr 2009; 48:4 doi: 10.1177/0009922808330781.
  7. HYPERLINK «http://www.uptodate.com.ololo.sci-hub.io/contents/ethanol-intoxication-inchildren-epidemiology-estimation-of-toxicity-andtoxic-effects/abstract/4» Engel J.S., Spiller H.A. Acute ethanol poisoning in a 4-year-old as a result of ethanol-based hand-sanitizer ingestion. Pediatr Emerg Care 2010; 26: 508-5 doi: 10.1097/PEC.0b013e3181e5bfc9.
  8. HYPERLINK «http://www.uptodate.com.ololo.sci-hub.io/contents/ethanol-intoxication-inchildren-epidemiology-estimation-of-toxicity-andtoxic-effects/abstract/5» Valeur K.S., Hertel S.A., Lundstrøm K.E., Holst H. Safe excipient exposure in neonates and small children - protocol for the SEEN project. Dan Med J 2017; Feb; 64(2). PMID: 28157063.
  9. Pichler G., Grubbauer H., Scheer P. et al. Monatsschr Kinderheilkd 1999 147: 947- 9
  10. Tõnisson M., Tillmann V., Kuudeberg A., Lepik D., Väli M. Acute Alcohol Intoxication Characteristics in Children, Alcohol and Alcoholism, 2013, 390-395, doi: 10.1093/alcalc/agt036.
  11. Fandler E., Scheer P., Rödl S. et al. Monatsschr Kinderheilkd (2008) 156: 591-6 doi: 10.1007/s00112-008-1750-
  12. Klevno V.A., Maksimov A.V., Kononov R.V., Krupina N.A. Forensic medical evaluation of the toxic action of ethanol in children. Journal of Forensic medicine. 2017; 3:3: 4 http://dx.doi.org/10.19048/2411-8729-2017-3-3-4-12.
  13. Vasiliev V.Yu., Ostapenko Yu.N., Livanov A.S., Soldatova V.Yu. Alcohol poisoning in adolescence. In the book.: Materials of the All-Russian scientific and practical conference «Problems of drug toxicology: from toxicological resuscitation to drug rehabilitation». S-Petersburg. Alta Astra Ltd., 2016; (in Russian).

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