ASSESSMENT OF TOXICITY AND HAZARD OF TECHNICAL PRODUCT OF TRIAZINONE’S DERIVATIVE

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Abstract

Experimental assessment of toxicity and hazard of technical product of triazinone’s derivative at its peroral administration into warm-blooded animals’ bodies (male rats) has been conducted to determine the character of the substance biological action. Its acute peroral toxicity was at the level of LD50 -1693 ± 470 mg/kg of body weight, hazard class – 4 according to Hygienic Classification of Pesticides (Sanitary Rules & Standards 1.2.2584-10). Effective dose was 62.5 mg/kg b.w., non-effective dose (NOEL) was 12.5 mg/kg b.w. ADI was 0.1 mg/kg b.w.

About the authors

V. N. Rakitskii

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Author for correspondence.
Email: pesticidi@yandex.ru

Rakitskii Valery Nikolaevich 

141014, Mytishchi, Moscow Region,

Russian Federation

T. M. Еpishina

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@yandex.ru

Epishina Tatiana Mihailovna

141014, Mytishchi, Moscow Region,

Russian Federation

E. G. Chkhvirkiya

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@yandex.ru

Chkhvirkiya Elena Grigor'evna

141014, Mytishchi, Moscow Region,

Russian Federation

T A. Sinitskaya

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@yandex.ru

Sinitskaya Tat'yana Alekseevna

141014, Mytishchi, Moscow Region,

Russian Federation

Е. A. Mukhina

.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@yandex.ru

Mukhina Ekaterina Aleksandrovna

141014, Mytishchi, Moscow Region,

Russian Federation

References

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Copyright (c) 2019 Rakitskii V.N., Еpishina T.M., Chkhvirkiya E.G., Sinitskaya T.A., Mukhina Е.A.


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