Stimulation of Mesenchymal Stem Cells Proliferation from the Femur of Wistar Rats by Nanosecond Microwave Radiation: Dependence on the Number of Pulses

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Abstract

The effect of nanosecond repetitively pulsed microwave radiation (RPM, 50–4000 pulses, pulse repetition rate of 13 Hz, peak power flux density of 140 W/cm2, carrier frequency of 10 GHz) on the stimulation of me-senchymal stem cells (MSC) proliferation was studied. The effect of exposure was assessed by the change in the number of cells in the culture after a single irradiation with a different number of pulses. The most pronounced effect exerted by the impact with 100 and 50 pulses, and the effect is realized with a maximum speed after 24 hours.

About the authors

А. А. Gostyuhina

Institute of High Current Electronics, Siberian Branch of the Russian Academy of Sciences; Federal Scientific and Clinical Center of Medical Rehabilitation and
Balneology of the Federal Medical and Biological Agency of Russia; National Research Tomsk State University

Email: kereya21@mail.ru
Russia, Tomsk; Russia, Moscow; Russia, Tomsk

М. А. Bolshakov

Institute of High Current Electronics, Siberian Branch of the Russian Academy of Sciences; National Research Tomsk State University

Email: kereya21@mail.ru
Russia, Tomsk; Russia, Tomsk

А. V. Samoylova

Institute of High Current Electronics, Siberian Branch of the Russian Academy of Sciences; National Research Tomsk State University; Siberian State Medical University of the Ministry of Health of the Russian Federation

Author for correspondence.
Email: kereya21@mail.ru
Russia, Tomsk; Russia, Tomsk; Russia, Tomsk

O. S. Doroshenko

Federal Scientific and Clinical Center of Medical Rehabilitation and
Balneology of the Federal Medical and Biological Agency of Russia; National Research Tomsk State University

Email: kereya21@mail.ru
Russia, Moscow; Russia, Tomsk

M. V. Svetlik

National Research Tomsk State University; Siberian State Medical University of the Ministry of Health of the Russian Federation

Email: kereya21@mail.ru
Russia, Tomsk; Russia, Tomsk

О. P. Kutenkov

Institute of High Current Electronics, Siberian Branch of the Russian Academy of Sciences

Email: kereya21@mail.ru
Russia, Tomsk

K. V. Zaitsev

Federal Scientific and Clinical Center of Medical Rehabilitation and
Balneology of the Federal Medical and Biological Agency of Russia

Email: kereya21@mail.ru
Russia, Moscow

V. V. Rostov

Institute of High Current Electronics, Siberian Branch of the Russian Academy of Sciences

Email: kereya21@mail.ru
Russia, Tomsk

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Copyright (c) 2023 А.А. Гостюхина, М.А. Большаков, А.В. Самойлова, О.С. Дорошенко, М. В. Светлик, О.П. Кутенков, К.В. Зайцев, В.В. Ростов