Mechanisms of Stem Cells and Their Secreted Exosomes in the Treatment of Autoimmune Diseases


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Abstract

:Stem cells play a therapeutic role in many diseases by virtue of their strong self-renewal and differentiation abilities, especially in the treatment of autoimmune diseases. At present, the mechanism of the stem cell treatment of autoimmune diseases mainly relies on their immune regulation ability, regulating the number and function of auxiliary cells, anti-inflammatory factors and proinflammatory factors in patients to reduce inflammation. On the other hand, the stem cell- derived secretory body has weak immunogenicity and low molecular weight, can target the site of injury, and can extend the length of its active time in the patient after combining it with the composite material. Therefore, the role of secretory bodies in the stem cell treatment of autoimmune diseases is increasingly important.

About the authors

Shu-Qian Lin

, Clinical College of the 920th Hospital of Kunming Medical University

Email: info@benthamscience.net

Kai Wang

, Clinical College of the 920th Hospital of Kunming Medical University

Email: info@benthamscience.net

Xing-Hua Pan

Basic medical laboratory, 920 Hospital of Joint Logistic Support Force of the Chinese People Liberation Army

Email: info@benthamscience.net

Guang-Ping Ruan

Basic medical laboratory, 920 Hospital of Joint Logistic Support Force of the Chinese People Liberation Army

Author for correspondence.
Email: info@benthamscience.net

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