Email this article Structure of corneal opacities in children in a specialized hospital practice
- Authors: Mamakaeva I.R.1, Pleskova A.V.1, Katargina L.A.1
-
Affiliations:
- Helmholtz National Medical Research Center of Eye Diseases
- Issue: Vol 16, No 4 (2021)
- Pages: 5-11
- Section: Original study article
- Published: 25.12.2021
- URL: https://ruspoj.com/1993-1859/article/view/84509
- DOI: https://doi.org/10.17816/rpoj84509
- ID: 84509
Cite item
Open Access
Access granted
Abstract
AIM: To evaluate the nosological structure of various etiologies in a specialized pediatric ophthalmosurgical center for 5 years (from 2016 to 2020)
MATERIAL AND METHODS: This prospective study was conducted at the Department of Eye Pathology in Children of the Helmholtz Moscow Research Institute of Eye Diseases from January 01, 2016, to December 31, 2020, and collected and summarized clinical observations in children with corneal opacity (CO) of various etiologies. Statistical annual reports and case histories of children who were hospitalized in the pediatric surgical department were analyzed. The analysis of discharge epicrisis was conducted only in children with corneal changes of various natures.
RESULTS: The proportion of children with corneal opacities from 2016 to 2020 was 13.5% (954 children out of 7066 hospitalized). Secondary CO was determined in most cases and amounted to 75.2%. The leading nosologies were congenital corneal opacities (24.8%), post-traumatic changes (33.6%), and post-inflammatory corneal degenerations (37.1%). Penetrating keratoplasty was more often performed in congenital pathology (55.8%), and scarification was more often used in the group of children with postuveal CO (96.3%).
CONCLUSION: Corneal opacities in children have a significant role in the overall structure of the visual organ pathology in children and have a large polymorphism. CO was secondary in the vast majority of children. Therefore, methods of CO prevention were searched. The general nosological structure did not undergo significant fluctuations throughout the study period.
Keywords
Full Text
About the authors
Indira R. Mamakaeva
Helmholtz National Medical Research Center of Eye Diseases
Author for correspondence.
Email: imamakaeva@mail.ru
ORCID iD: 0000-0003-0874-6504
MD, PhD, Researcher
Russian Federation, 14/19, Sadovaya-Chernogriazskaya street, Moscow, 105062Alla V. Pleskova
Helmholtz National Medical Research Center of Eye Diseases
Email: dho@igb.ru
ORCID iD: 0000-0002-4458-4605
MD, Dr. Med. Sciences
Russian Federation, 14/19, Sadovaya-Chernogriazskaya street, Moscow, 105062Lyudmila A. Katargina
Helmholtz National Medical Research Center of Eye Diseases
Email: katargina@igb.ru
ORCID iD: 0000-0002-4857-0374
MD, Dr. Med. Sciences, Professor
Russian Federation, 14/19, Sadovaya-Chernogriazskaya street, Moscow, 105062References
- Katargina LA, Mikhaylova LA. The state of the children’s ophthalmological service in the Russian Federation (2012-2013). Russian pediatric ophthalmology. 2015;10(1):5–10. (In Russ).
- Katargina LA, Brzheskij VV, Guseva MR, et al. Federal clinical guidelines «Diagnosis and treatment of uveitis associated with juvenile idiopathic arthritis». Russian pediatric ophthalmology. 2016;11(2):2–111. (In Russ).
- Pleskova AV, Mazanova EV, Sorokin AA. Topical issues of differential diagnosis and tactics of treatment of congenital corneal opacities in children. Oftal’mokhirurgiya. 2021;(1):73–81. (In Russ). doi: 10.25276/0235-4160-2021-1-73-81
- Sozurakova EA, Gromakina EV, Mozes VG. Modern concepts of inflammation and regeneration in penetrating corneal injuries. Oftal’mologiya. 2020;17(2):181–187. (In Russ). doi: 10.18008/1816-5095-2020-2-181-187
- Pleskova AV. The nosological structure of corneal opacities in children: an excursion into history. Russian pediatric ophthalmology. 2014;(2):39–43 (In Russ).
- Hovlykke M, Hjortdal J, Ehlers N, Nielsen K. Clinical results of 40 years of paediatric keratoplasty in a single university eye clinic. Acta Ophthalmol. 2014;92(4):370–377. doi: 10.1111/aos.12198x
- Yang LL, Lambert SR, Drews-Botsch C, Stulting RD. Long-term visual outcome of penetrating keratoplasty in infants and children with Peters anomaly. J AAPOS. 2009;13(2):175–180. doi: 10.1016/j.jaapos.2008.10.007
- Nischal KK. Congenital corneal opacities — a surgical approach to nomenclature and classification. Eye (Lond). 2007;21(10):1326–1337. doi: 10.1038/sj.eye.6702840
- Elbaz U, Strungaru H, Mireskandari K, et al. Long-Term Visual Outcomes and Clinical Course of Patients With Peters Anomaly. Cornea. 2021;40(7):822–830. doi: 10.1097/ICO.0000000000002577
- Aab EL, Aaby A, Bloom JN, et al. Diseases of the cornea, anterior segment, and Iris. Basic and Clinical Science Course, Section 6. Pediatric Ophthalmology and Strabismus. 2014.
- Karadag R, Rapuano CJ, Hammersmith KM, Nagra PK. Causes of congenital corneal opacities and their management in a tertiary care center. Arq Bras Oftalmol. 2020;83(2):98–102. doi: 10.5935/0004-2749.20200023
- Cillino S, Casuccio A, Di Pace F, et al. A five-year retrospective study of the epidemiological characteristics and visual outcomes of patients hospitalized for ocular trauma in a Mediterranean area. BMC Ophthalmol. 2008;8:6. doi: 10.1186/1471-2415-8-6
- Pohlmann D, Rossel M, Salchow DJ, Bertelmann E. Outcome of a penetrating keratoplasty in a 3-month-old child with sclerocornea. GMS Ophthalmol Cases. 2020;10:Doc35. doi: 10.3205/oc000162
- Nascimento H, Yasuta MK, Marquezan MC, et al. Uveitic band keratopathy: child and adult. J Ophthalmic Inflamm Infect. 2015;5(1):35. doi: 10.1186/s12348-015-0062-z
- Maharana PK, Nawaz S, Singhal D, et al. Causes and Management Outcomes of Acquired Corneal Opacity in a Preschool Age (0–5 Years) Group: A Hospital-Based Study. Cornea. 2019;38(7):868–872. doi: 10.1097/ICO.0000000000001962
Supplementary files
