Frequency of myopia development after congenital cataract extraction in infancy with different keratometric and biometric parameters in pseudophakic eyes
- Authors: Kruglova T.B.1, Egiyan N.S.1, Mamykina A.S.1, Katargina L.A.1
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Affiliations:
- Helmholtz National Medical Research Center of Eye Diseases
- Issue: Vol 15, No 3 (2020)
- Pages: 11-16
- Section: Clinical studies
- URL: https://ruspoj.com/1993-1859/article/view/47366
- DOI: https://doi.org/10.17816/rpo2020-15-3-11-16
- ID: 47366
Cite item
Abstract
Aim. In most children, unplanned myopia develops after the extraction of congenital cataracts (CC) with t he implantation of intraocular lenses (IOLs) in infancy; thus, it is necessary to analyze the mechanisms of its development.
The study aimed to investigate the role of keratometric and biometric indicators of eyes in pediatric patients with pseudophakia in the formation of myopia.
Material and methods. Analysis of refraction indices, degree of postoperative astigmatism, and length of the anteroposterior axis (APO) was performed in 40 pediatric patients (56 eyes) with bilateral (29 children, 45 eyes) and unilateral (11 children) pseudophakia at the age of 4 to 8 years after CC extraction with IOL implantation in infancy.
Results. Myopia was detected in 67.9% (38 eyes, 28 children) of cases, including 41.1% (23 eyes, 16 children) with moderate (12 eyes) and high (11 eyes) myopia. The study revealed a direct average correlation between the magnitude of astigmatism and the degree of developing myopia. Astigmatism of >3.25 diopters was detected frequently in moderate and high myopia. For eyes with astigmatism of >3.25 diopters, the APO length was 22.6 ± 1.9 mm (21.8–23.5 mm), whereas for those with astigmatism of <3.0 diopters, it was 20.9 ± 1.8 mm (20.3–21.5 mm). With the initial APO length of <20.0 mm, less eye growth was registered in the postoperative period.
Conclusion. In the majority of pediatric patients with pseudophakia, myopic refraction develops after CC extraction in infancy, which is influenced by the degree of astigmatism and the initial values of the APO length. Astigmatism of >3.0 diopters causes irregular peripheral defocus on the retina, which contributes to the overgrowth of the eye with pseudophakia after early CC extraction, leading to axial myopia. In CC eyes, the risk of myopia is lower with an initial APO length of <20.0 mm.
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About the authors
Tat’yana B. Kruglova
Helmholtz National Medical Research Center of Eye Diseases
Email: krugtb@yandex.ru
ORCID iD: 0000-0003-4193-681X
Dr of Med. Sci, Professor
Russian Federation, 105062, MoscowNaira S. Egiyan
Helmholtz National Medical Research Center of Eye Diseases
Email: nairadom@mail.ru
ORCID iD: 0000-0001-9906-4706
MD, PhD
Russian Federation, 105062, MoscowAleksandra S. Mamykina
Helmholtz National Medical Research Center of Eye Diseases
Author for correspondence.
Email: alexandraugust1@gmail.com
ORCID iD: 0000-0003-3521-6381
MD
Russian Federation, 105062, MoscowLyudmila A. Katargina
Helmholtz National Medical Research Center of Eye Diseases
Email: katargina@igb.ru
ORCID iD: 0000-0002-4857-0374
Dr of Med. Sci, Professor
Russian Federation, 105062, MoscowReferences
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