Email this article PATHOMORPHISM IN MEIBOMIAN GLANDS UNDER PHYSIOTHERAPEUTIC FACTOR AND SOME MEDICATIONS IMPACT UNDER THE EXPERIMENTAL HYPOOESTROGENIA CONDITIONS
- Authors: Obrubov SA1, Stavitskaya GV1, Dreval AA1, Obrubov AS1, Obrubova GA1, Boginskaya OA1
-
Affiliations:
- Issue: Vol 5, No 2 (2010)
- Pages: 38-41
- Section: Articles
- URL: https://ruspoj.com/1993-1859/article/view/37460
- DOI: https://doi.org/10.17816/rpoj37460
- ID: 37460
Cite item
Full Text
Abstract
Pathomorphism in meibomian glands in physiotherapeutic factor and some medications impact under experimental hypooestrogenia conditions was studied.
It was established that morphologic changes of meibomian glands have unidirectional character. The estrogenic medication Divigel is of most influence on the increase of the secretory follicles quantity and increase of the Malpighian layer of secretory follicles epithelium. The application of suis-organ preparation of estrogenic action (ovarium compositum) and impact by the pulse low-frequency electromagnetic field on the area of the animal's head has the most influence on the changes of microcirculatory bloodstream.
It was established that morphologic changes of meibomian glands have unidirectional character. The estrogenic medication Divigel is of most influence on the increase of the secretory follicles quantity and increase of the Malpighian layer of secretory follicles epithelium. The application of suis-organ preparation of estrogenic action (ovarium compositum) and impact by the pulse low-frequency electromagnetic field on the area of the animal's head has the most influence on the changes of microcirculatory bloodstream.
References
- Бржевский В. В., Садовникова Н. Н. Значение половых стероидных гормонов в развитии синдрома "сухого глаза" // Сборник науч. трудов V Всероссийской школы офтальмолога. - М., 2006. - С. 442-449.
- Akramian J., Wedrich A., Nepp J., Sator M. Estrogen therapy in keratoconjunctivitis sicca // Adv. Exp. Med. Biol. - 1998. - Vol. 438. - P. 1005-1009.
- Gutgesell V. J., Stern G. A., Hood C. I. Histopathology of Meibomian gland dysfunction // Am. J. Ophthalmol. - 1982. - Vol. 94. - P. 393-387.
- Mathers W. D. Meibomian gland disease // Dry Eye and Ocular Surface Disorders / Eds S. C. Pflugfelder et al. - New York; Basel, 2004. - P. 247-268.
- Sator M. O., Golaszewsky T., Gruber D. Extragenital effects of hormone replacement therapy // IV European Congress on Menopause. - Viena, 1997. - P. 46.
- Sator M. O., Joura E. A. Treatment of menopausal keratoconjunctivitis sicca with topical oestradiol // Br. J. Obstetr. Gynaecol. - 1998. - Vol. 105. - P. 100-102.
- Schaumberg D. A., Buring J. E., Sullivan D. A., Dana M. R. Hormone replacement therapy and the prevalence of dry eye syndrome // J. A. M. A. - 2001. - Vol. 286. - P. 2114- 2119.
- Sullivan D. A., Edwards J. A. Androgen stimaulation of lacrimal gland function in mouse models of Sjögren syndrome // J. Steroid Biochem. Mol. Biol. - 1997. - Vol. 60. - P. 237-245.
- Sullivan D. A., Wickham L. A., Rocha E. M. et al. Influence of gender, sex steroid hormones and the hypothalamic-pituitary axic on the structure and function of the lacrimal gland // Adv. Exp. Med. Biol. - 1998. - Vol. 438. - P. 11-42.
- Sullivan D. A., Krenzer K. L., Sullivan B. D. Does androgen insufficiency cause lacrimal gland inflammation and aqueous tear deficiency? // Invest. Ophthalmol. Vis. Sci. - 1999. - Vol. 40. - P. 1261-1265.
- Sullivan D. A., Wickham L. A., Rochba E. M. Androgens and dry eye in Sjgren syndrome // Ann. N. Y. Acad. Sci. - 1999. - Vol. 876. - P. 312-324.
- Sullivan D. A., Sullivan B. D., Ullman M. D. et al. Androgen influence on the Meibomian gland // Invest. Ophthalmol. Vis. Sci. - 2000. - Vol. 41, N 12. - P. 3732-3742.
- Sullian B. D., Evans J. E., Cermak J. M. et al. Complete androgen insensivity syndrom // Arch. Ophthalmol. - 2002. - Vol. 120. - P. 1689-1699.
Supplementary files
