Structure of corneal opacities in children in a specialized hospital practice

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AIM: To evaluate the nosological structure of various etiologies in a specialized pediatric ophthalmosurgical center for 5 years (from 2016 to 2020)

MATERIAL AND METHODS: This prospective study was conducted at the Department of Eye Pathology in Children of the Helmholtz Moscow Research Institute of Eye Diseases from January 01, 2016, to December 31, 2020, and collected and summarized clinical observations in children with corneal opacity (CO) of various etiologies. Statistical annual reports and case histories of children who were hospitalized in the pediatric surgical department were analyzed. The analysis of discharge epicrisis was conducted only in children with corneal changes of various natures.

RESULTS: The proportion of children with corneal opacities from 2016 to 2020 was 13.5% (954 children out of 7066 hospitalized). Secondary CO was determined in most cases and amounted to 75.2%. The leading nosologies were congenital corneal opacities (24.8%), post-traumatic changes (33.6%), and post-inflammatory corneal degenerations (37.1%). Penetrating keratoplasty was more often performed in congenital pathology (55.8%), and scarification was more often used in the group of children with postuveal CO (96.3%).

CONCLUSION: Corneal opacities in children have a significant role in the overall structure of the visual organ pathology in children and have a large polymorphism. CO was secondary in the vast majority of children. Therefore, methods of CO prevention were searched. The general nosological structure did not undergo significant fluctuations throughout the study period.

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作者简介

Indira Mamakaeva

Helmholtz National Medical Research Center of Eye Diseases

编辑信件的主要联系方式.
Email: imamakaeva@mail.ru
ORCID iD: 0000-0003-0874-6504

MD, PhD, Researcher

俄罗斯联邦, 14/19, Sadovaya-Chernogriazskaya street, Moscow, 105062

Alla Pleskova

Helmholtz National Medical Research Center of Eye Diseases

Email: dho@igb.ru
ORCID iD: 0000-0002-4458-4605

MD, Dr. Med. Sciences

俄罗斯联邦, 14/19, Sadovaya-Chernogriazskaya street, Moscow, 105062

Lyudmila Katargina

Helmholtz National Medical Research Center of Eye Diseases

Email: katargina@igb.ru
ORCID iD: 0000-0002-4857-0374

MD, Dr. Med. Sciences, Professor

俄罗斯联邦, 14/19, Sadovaya-Chernogriazskaya street, Moscow, 105062

参考

  1. Katargina LA, Mikhaylova LA. The state of the children’s ophthalmological service in the Russian Federation (2012-2013). Russian pediatric ophthalmology. 2015;10(1):5–10. (In Russ).
  2. Katargina LA, Brzheskij VV, Guseva MR, et al. Federal clinical guidelines «Diagnosis and treatment of uveitis associated with juvenile idiopathic arthritis». Russian pediatric ophthalmology. 2016;11(2):2–111. (In Russ).
  3. Pleskova AV, Mazanova EV, Sorokin AA. Topical issues of differential diagnosis and tactics of treatment of congenital corneal opacities in children. Oftal’mokhirurgiya. 2021;(1):73–81. (In Russ). doi: 10.25276/0235-4160-2021-1-73-81
  4. Sozurakova EA, Gromakina EV, Mozes VG. Modern concepts of inflammation and regeneration in penetrating corneal injuries. Oftal’mologiya. 2020;17(2):181–187. (In Russ). doi: 10.18008/1816-5095-2020-2-181-187
  5. Pleskova AV. The nosological structure of corneal opacities in children: an excursion into history. Russian pediatric ophthalmology. 2014;(2):39–43 (In Russ).
  6. Hovlykke M, Hjortdal J, Ehlers N, Nielsen K. Clinical results of 40 years of paediatric keratoplasty in a single university eye clinic. Acta Ophthalmol. 2014;92(4):370–377. doi: 10.1111/aos.12198x
  7. Yang LL, Lambert SR, Drews-Botsch C, Stulting RD. Long-term visual outcome of penetrating keratoplasty in infants and children with Peters anomaly. J AAPOS. 2009;13(2):175–180. doi: 10.1016/j.jaapos.2008.10.007
  8. Nischal KK. Congenital corneal opacities — a surgical approach to nomenclature and classification. Eye (Lond). 2007;21(10):1326–1337. doi: 10.1038/sj.eye.6702840
  9. Elbaz U, Strungaru H, Mireskandari K, et al. Long-Term Visual Outcomes and Clinical Course of Patients With Peters Anomaly. Cornea. 2021;40(7):822–830. doi: 10.1097/ICO.0000000000002577
  10. Aab EL, Aaby A, Bloom JN, et al. Diseases of the cornea, anterior segment, and Iris. Basic and Clinical Science Course, Section 6. Pediatric Ophthalmology and Strabismus. 2014.
  11. Karadag R, Rapuano CJ, Hammersmith KM, Nagra PK. Causes of congenital corneal opacities and their management in a tertiary care center. Arq Bras Oftalmol. 2020;83(2):98–102. doi: 10.5935/0004-2749.20200023
  12. Cillino S, Casuccio A, Di Pace F, et al. A five-year retrospective study of the epidemiological characteristics and visual outcomes of patients hospitalized for ocular trauma in a Mediterranean area. BMC Ophthalmol. 2008;8:6. doi: 10.1186/1471-2415-8-6
  13. Pohlmann D, Rossel M, Salchow DJ, Bertelmann E. Outcome of a penetrating keratoplasty in a 3-month-old child with sclerocornea. GMS Ophthalmol Cases. 2020;10:Doc35. doi: 10.3205/oc000162
  14. Nascimento H, Yasuta MK, Marquezan MC, et al. Uveitic band keratopathy: child and adult. J Ophthalmic Inflamm Infect. 2015;5(1):35. doi: 10.1186/s12348-015-0062-z
  15. Maharana PK, Nawaz S, Singhal D, et al. Causes and Management Outcomes of Acquired Corneal Opacity in a Preschool Age (0–5 Years) Group: A Hospital-Based Study. Cornea. 2019;38(7):868–872. doi: 10.1097/ICO.0000000000001962

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