Results of corneal collagen crosslinking in children and adolescents with keratoconus I-III stage

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Aim. To estimate effectiveness and results of Corneal collagen crosslinking keratoconus treatment in children in a year after the treatment.

Material and methods. 15 patients (21 eyes ) aged 11-18 with keratoconus I-III st. were studied before the CXL and a year after the surgery. We compared their data of standart ophthalmological and deep keratotopographic investigations, included best corrected and uncorrected VA, keratometry, pachimetry, refraction, corneal OCT e.t.c.

Results. No intra- or postoperative complications were observed. In a year after CXL we found statistically significant improve in VA (uncorrected and best corrected) in children, stability and improvement of corneal characteristics as decrease in SE of myopia and stabilization of all topographic indices.

Conclusion. CXL is a safe and effective method for the stabilization of progressive keratoconus in children. It halted disease and improves corneal topography and visual functions in children and adolescents. But we should manage such patients very carefully as keratoconus in children tends to be more aggressive and unpredictable in its progression.

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About the authors

Kristina K. Shefer

The S. Fyodorov Eye Microsurgery Federal State Institution; North-Western State Medical University named after I.I. Mechnikov

Author for correspondence.
ORCID iD: 0000-0003-0568-6593


Russian Federation, Saint Petersburg; Saint Petersburg

Dilara R. Mirsaitova

The S. Fyodorov Eye Microsurgery Federal State Institution

ORCID iD: 0000-0002-8825-312X


Russian Federation, Saint Petersburg

Aleksey V. Titov

The S. Fyodorov Eye Microsurgery Federal State Institution

ORCID iD: 0000-0001-6847-4737


Russian Federation, Saint Petersburg


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