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A case of congenital glaucoma in type I neurofibromatosis
- Authors: Pleskova A.V.1, Lugovkina K.V.1, Panova A.Y.1, Sorokin A.A.1
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Affiliations:
- Helmholtz National Medical Research Center of Eye Diseases
- Issue: Vol 16, No 3 (2021)
- Pages: 37-42
- Section: Клинический случай
- URL: https://ruspoj.com/1993-1859/article/view/79195
- DOI: https://doi.org/10.17816/rpoj79195
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Abstract
BACKGROUND: Recklinghausen’s generalized neurofibromatosis (NF) is a hereditary disease characterized by the formation of benign tumors from the nervous tissue that provokes skin and bone changes of various types. Often, involvement in the pathological process and the organ of vision. The variability of eye lesions in NF-I type is known according to the clinical course, severity, and clinical forms. Gliomas and atrophy of the optic nerves, neurofibromas in the iris, sclera, conjunctiva, eyelids, less often — glaucoma, buphthalmos, orbital osteodystrophy are described.
RESULTS: The article describes a rare case of type I neurofibromatosis, the first clinical manifestation of congenital glaucoma. Modern complex ophthalmological examination made it possible to identify the cause and clarify the nature of the development of glaucoma.
CONCLUSION: The need for an interdisciplinary approach to the diagnosis, dispensary observation, and treatment of NF-I is emphasized.
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About the authors
A. V. Pleskova
Helmholtz National Medical Research Center of Eye Diseases
Email: dho@igb.ru
ORCID iD: 0000-0002-4458-4605
MD, Dr. Med. Sciences
Russian Federation, MoscowK. V. Lugovkina
Helmholtz National Medical Research Center of Eye Diseases
Email: ksushalyg@mail.ru
ORCID iD: 0000-0002-3531-3846
MD, PhD, Researcher
Russian Federation, MoscowAnna Yu. Panova
Helmholtz National Medical Research Center of Eye Diseases
Email: annie_panova18@mail.ru
ORCID iD: 0000-0003-2103-1570
SPIN-code: 9930-4813
MD, PhD
Russian Federation, MoscowA. A. Sorokin
Helmholtz National Medical Research Center of Eye Diseases
Author for correspondence.
Email: a.a.sorokin@inbox.ru
ORCID iD: 0000-0002-8213-8518
PhD student
Russian Federation, MoscowReferences
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